Hexarelin

Hexarelin API - Akopọ ọja

Hexarelinjẹ sintetikipeptide secretagogue homonu idagba (GHS)ati alagbaraGHSR-1a agonist, ni idagbasoke lati lowoitusilẹ homonu idagba endogenous (GH).. O jẹ ti awọnidile ghrelin mimeticati pe o ni awọn amino acids mẹfa (hexapeptide kan), ti o funni ni iduroṣinṣin ti iṣelọpọ agbara ati awọn ipa itusilẹ GH ti o lagbara ni akawe si awọn afọwọṣe iṣaaju bii GHRP-6.

Hexarelin jẹ iwadi lọpọlọpọ fun awọn ohun elo rẹ ninuendocrinology, isan jafara, atunṣe ọkan ọkan, ati awọn itọju ti ogbologbo, nitori agbara rẹ lati gbe GH soke nipa ti ara atiifosiwewe idagba bi insulini 1 (IGF-1)awọn ipele lai ṣe afihan awọn homonu ita taara.

Mechanism ti Action

Hexarelin sopọ si awọnolugba idagbasoke asiri homonu (GHSR-1a)lori pituitary ati hypothalamus, mimicking awọn iṣẹ tighrelin— ebi adayeba ti ara ati homonu ti n tu silẹ GH.

Awọn iṣe pataki ti ẹkọ-ara:

• Ṣe iwuri itusilẹ GH pulsatile

• Npọ si kaakiriIGF-1awọn ipele

• Awọn igbegaawọn ipa anabolic(idagbasoke iṣan, imularada)

• Awọn atilẹyinọra iṣelọpọatiisọdọtun sẹẹli

• Le ṣe afihancardioprotectiveatiegboogi-apoptoticawọn ipa

Ko dabi awọn peptides GHS miiran, Hexarelin ṣeKo ṣe alekun cortisol tabi prolactin ni pataki, laimu kan regede endocrine profaili.

Iwadi ati Agbara Iwosan

1. Growth ti iṣan & Imularada

• Awọn igbegatitẹ si apakan araidagbasoke

• Awọn ilọsiwajuisan titunṣe ati isọdọtun

• Kọ ẹkọ nisarcopenia, cachexia, ati imularada lẹhin-abẹ-abẹ

2. Idaabobo Ẹjẹ ọkan

• Awọn iwadii iṣaaju fihanilọsiwaju iṣẹ ọkan ọkanlẹhin ipalara myocardial

• Dinkufibrosis ọkan ọkanati awọn ilọsiwajuida ejection ventricular osi

• O pọju lilo ninuikuna okanatiokan ti ogboawọn awoṣe

3. Ọra Metabolism & Anti-Ogbo

• Awọn ilọsiwajulipolysisati awọn ilọsiwajuifamọ insulin

• Awọn atilẹyinawọn itọju ti ogbologbonipasẹ GH / IGF-1 axis fọwọkan

• Le ṣe iranlọwọ lati ṣetọjuiwuwo egungun ati ilera apapọ

Awọn ẹya API (Ẹgbẹ Gentolex)

• Mimọ ≥ 99%

• Ti ṣelọpọ nipasẹAsopọmọra peptide alakoso ti o lagbara (SPPS)

• GMP-bi awọn ajohunše, kekere endotoxin ati awọn iṣẹku olomi

• Ipese to rọ:R&D si iwọn iṣowo