Melanotan II

Melanotan II API

Melanotan IIjẹ afọwọṣe heptapeptide cyclic sintetiki tiα-melanocyte-ẹjẹ homonu ti o nmu (α-MSH), ni idagbasoke latimu melanogenesis ṣiṣẹ, mu daraIdaabobo UV, ati modulateibalopo ati awọn iṣẹ iṣelọpọ. O ìgbésẹ bi ati kii-aṣayan agonistti awọn olugba melanocortin, paapaaMC1R, MC3R, atiMC4R.

Ni akọkọ iwadi fun awọn oniwe-soradi soradiatiphotoprotective-ini, Melanotan II ti tun han ipa loriimudara libido, yanilenu bomole, atiiwontunwonsi agbara, ṣiṣe awọn ti o kan multifunctional iwadi peptide pẹlu anfani ni dermatology, endocrinology, ati ibalopo oogun.

Mechanism ti Action

Melanotan II ṣiṣẹ nipa mimuuṣiṣẹpọ ọpọlọpọ awọn olugba melanocortin:

• MC1R: Awọn iwuriiṣelọpọ melanin→ pọ si pigmentation awọ ara ati aabo UV

• MC3R / MC4R: lowo ninuyanilenu Iṣakoso, imudara libido, atihomeostasis agbara

• Rekọja idena-ọpọlọ ẹjẹ, ti o ni ipa awọn ipa ọna neurohormonal aarin

Iwadi ati Awọn ohun elo ti o pọju

Botilẹjẹpe ko fọwọsi fun lilo iṣoogun, Melanotan II jẹ iwadi lọpọlọpọ fun atẹle naa:

1. Pigmentation awọ & Idaabobo UV

• Awọn igbegaeumelanin kolaginni, yori siadayeba soradi

• PeseFọto-aabo awọn ipalaisi ifihan oorun

• O pọju fun idinku eewu akàn ara ni awọn ẹni-kọọkan ti o ni awọ ododo

2. Ibalopo Ibalopọ

• Afihan simu libido ati ibalopo arousalninu ati ọkunrin ati obinrin

• Ti kọ ẹkọ bi itọju ailera ti o pọju funaiṣiṣẹ erectile (ED)nipasẹ MC4R ibere ise

3. yanilenu & iwuwo Management

• Maydin yanilenu ati ounje gbigbeminipa sise lori awọn ipa ọna hypothalamic

• O pọju adjunct niisanraju iwadi

Awọn ẹya API (nipasẹ Ẹgbẹ Gentolex)

• Mimo giga ≥ 99%(HPLC & LC-MS timo)

• Synthesized nipasẹAsopọmọra peptide alakoso-lile (SPPS)

• Kekere endotoxin, awọn olomi aloku kekere

• Wa ninuR&D si iwọn iṣowo