Boc-His (Trt) -Aib-Gln (Trt)-Gly-OH

Boc-His (Trt) -Aib-Gln (Trt)-Gly-OH

Ohun elo Iwadi:
Tetrapeptide ti o ni aabo yii ni a lo ninu iṣelọpọ peptide ati awọn ẹkọ ibaramu. Ijọpọ Aib (α-aminoisobutyric acid) gba awọn oniwadi laaye lati ṣe iwadii awọn ẹya helical ati ihuwasi kika ni awọn peptides kukuru. Awọn ẹgbẹ iṣẹ-ṣiṣe ti o ni aabo (Boc, Trt) ṣe idaniloju iduroṣinṣin ati yiyan lakoko iṣelọpọ peptide ti o lagbara, ti o jẹ ki o jẹ awoṣe ti o niyelori fun kikọ ẹkọ awọn adaṣe ẹhin peptide ati awọn ibaraẹnisọrọ ẹgbẹ-ẹgbẹ.

Iṣẹ:
Boc-His (Trt) -Aib-Gln (Trt) - Gly-OH n ṣiṣẹ gẹgẹbi apẹrẹ awoṣe fun ṣawari iduroṣinṣin peptide ati awọn ilana iṣeto. Aib ṣe alabapin si imuduro helical, lakoko ti awọn iṣẹku histidine ati glutamine pese awọn aaye ibaraenisepo ti o pọju, ti o wulo ni sisọ awọn peptides bioactive tabi ṣiṣe awọn ajẹkù amuaradagba. O tun le jẹ aṣaaju fun awọn peptides iṣẹ ni idagbasoke oogun tabi awọn igbelewọn biokemika.