Daptomini 103060-53-3 fun awọn arun aarun
Awọn alaye ọja
| Orukọ | Daptomycin |
| Nọmba Com | 103060-53-3 |
| Alolacular agbekalẹ | C72h101N17O26 |
| Iwuwo Molucular | 1620.67 |
| Nọmba Einecs | 600-389-2 |
| Yo ojuami | 202-204 ° C |
| Farabale | 2078.2 ± 65.0 ° C (asọtẹlẹ) |
| Oriri | 1.45 ± 0.1 g / cm3 (asọtẹlẹ) |
| oju filaṣi | 87 ℃ |
| Awọn ipo ipamọ | Ti dido ni gbẹ, fipamọ ni firisa, labẹ -20 ° C |
| Oogun | Methanol: Soluble6mg / ML |
| Onigbọwọ | (PKA) 4.00 ± 0.10 (asọtẹlẹ) |
| Irisi | iyẹfun |
| Awọ | ti ko ni awọ si fifin |
Awọn isopọmọra
N- [la (1-Oxodecl)-Trp-d-asn-l-asp -] - Cyclo [l-thly-l-asp-l-asp-l-asp- Gly-d-sE - [(3R) -3 -3-Meslu -] - 4-) D-asn-asp -] - cyclo [Th * -gly-l-asp-lly-lly-lly-lly-gly-gly-d-metlyl-l Glu -] - 3- (2 -minoBnzyl) -l-Ala -]; n- Oxpecy) - α-asborty-d-alanyl-l-α-aspartylcyl-d-horylcycylcylcylcy -3 - 3-gumtamy-γ, 2-gulumo-γ, 2-gulumo-γ, 2-4enebuutooicid (13-4) lacone; Daptominice; Dapcin; Dapcin; Dapcinciin,> = 99%; daptomycingeadestesutesodesmadesmadesmades; Daptomycin (LY146032))
Isapejuwe
Awọn apakokoro aporo banki jẹ eroja lipopeptitiofefe gigun kẹkẹ kan pẹlu browtestation ti ko ni idamu ti awọn irinna ogiri ti ko ni agbara ninu awo. Yiyipada awọn ohun-ini ti mertoplasmic membanman le ṣe idiwọ iṣẹ iṣẹ-ṣiṣe kokoro aisan ninu awọn ọna pupọ ati nyara awọn kokoro-ọja ti o muna. Ni afikun si agbara rẹ lati ṣe agbejade julọ julọ awọn kokoro-itọju gireally ti o yẹ ni idaabobo ṣe pataki julọ fun awọn iraka ti o ya sọtọ ti o han si igari, ati laini ni fitiro. O ni iṣẹ ṣiṣe ti o munadoko, ati ohun-ini yii ni awọn ilogun ile-iwosan pupọ fun awọn alaisan aisan ti o bajẹ. Arun ọlọjẹ eosinonia jẹ arun to ṣe pataki ati awọn aami aisan pẹlu iba, Ikọaláìdúró, ẹmi ti ẹmi, ati iṣoro ẹmi.
Ipa antibactellal
Daptomycin ni iṣẹ ṣiṣe balaini to dara lodi si awọn kokoro ọlọjẹ-sooro, gẹgẹbi ajile ọlọjẹ-urus, ati ogbonju Metukilccuous, ati mesa). Mic = 0.0625 ~ 1μG / ML fun awọn kokoro arun, Microc ti edepococcus jẹ 0,5 ~ 1μG / ML, ati Mic ti Stococcus Sooro si awọn egboogi glycopedictits jẹ 1 ~ 2μg / milimita.
