RU-58841 Ti a lo bi Idena Ipadanu Irun ati Pipa Apẹrẹ Ọkunrin
Alaye ọja
| Oruko | RU-58841 |
| nọmba CAS | 154992-24-2 |
| Ilana molikula | C17H18F3N3O3 |
| Ìwúwo molikula | 369.34 |
| Nọmba EINECS | 1592732-453-0 |
| Ojuami farabale | 493.6± 55.0 °C(Asọtẹlẹ) |
| iwuwo | 1.39 |
| Ipo ipamọ | Ti di ninu gbigbẹ, fipamọ sinu firisa, labẹ -20 ° C |
| Fọọmu | Lulú |
| Àwọ̀ | Funfun |
| Iṣakojọpọ | PE apo + Aluminiomu apo |
Awọn itumọ ọrọ sisọ
RU58841; 4- (4,4-Dimethyl-2,5-dioxo-3- (4-hydroxybutyl) 1-imidazolidinyl) -2- (trifluoromethyl) benzonitrile; 4- [3- (4-Hydroxybutyl) -4,4-dimethyl-2,5-dioxo-1-imidazolidinyl]-2-ben- (trifluoromethyl). onitrile; 4- [3- (4-Hydroxybutyl) -4,4-diMethyl-2,5-dioxoiMidazolidin-1-yl] -2- (trifluoroMethyl) ben zonitrile; RU-58841E: candyli (ni) speedgainpharma (aami) com; CS-637; RU588841; RU58841; RU58841; RU-58841
Pharmacological Ipa
Apejuwe
RU 58841 (PSK-3841) jẹ antagonist olugba androgen ti o ṣe agbega isọdọtun irun.RU58841 jẹ oogun iwadii ti a ṣẹda fun itọju lodi si alopecia androgenic, ti a tun mọ ni irun ori ọkunrin (MPD).
Gẹgẹbi egboogi-androgen ti agbegbe, ilana rẹ ti iṣe kii ṣe kanna bi ti finasteride. Finasteride taara ṣiṣẹ lori 5a reductase, ṣe idiwọ iyipada ti testosterone sinu DHT, ati dinku akoonu ti DHT ninu ara. RU58841 ṣe idiwọ olubasọrọ laarin dihydrotestosterone ati awọn olugba irun ori irun, kii ṣe taara akoonu DHT dinku, ṣugbọn o dinku asopọ ti DHT ati awọn olugba irun ti irun, ki o le ṣe aṣeyọri idi ti itọju androgenetic alopecia.
4-[3- (4-Hydroxybutyl) -4,4-dimethyl-2,5-dioxo-1-imidazolidinyl] -2- (trifluoromethyl) benzonitrile le ṣee lo bi oogun Kemikali synthesis intermediates.Ti 4-[3- (4-hydroxybutyl) -4,4-dimethyl-2,5-dioxo-1-imidazolidinyl] -2- (trifluoromethyl) benzonitrile ti wa ni ifasimu, Gbe alaisan lọ si afẹfẹ titun;Ni ọran ti ifarakan ara, yọ awọn aṣọ ti a ti doti kuro, fi omi ṣan awọ ara daradara pẹlu ọṣẹ ati omi, ki o wa itọju ilera ti aibalẹ ba waye;
Ipa ẹgbẹ
RU58841 ni a fi si ori awọ-ori, ti awọn irun irun ti nfa, ati ni imọran, o le wọ inu ẹjẹ ati ki o kan awọn ẹya ara miiran. Ṣugbọn ko si awọn ipa ẹgbẹ eto ti a rii ni awọn iwadii ti ohun elo agbegbe ni awọn obo. Sibẹsibẹ, diẹ ninu awọn eniyan ti o ti gbiyanju RU58841 beere pe wọn ti ni iriri diẹ ninu awọn ipa-ipa ti o ṣeeṣe lati lilo RU, pẹlu irritation awọ-ara, libido ti o dinku, aiṣedede erectile, ọgbun, oju pupa, dizziness, ati orififo.
