Cetrorelix Acetate lati Dena Tita Ovulation 120287-85-6
Apejuwe ọja
| Oruko | Cetrorelix acetate |
| nọmba CAS | 120287-85-6 |
| Ilana molikula | C70H92ClN17O14 |
| Ìwúwo molikula | 1431.04 |
| Nọmba EINECS | 686-384-6 |
Awọn itumọ ọrọ sisọ
AC-(D-ALA[3- (2-NAPHTHYL)])-[D-PHE(4-CL)]-(D-ALA[3- (3-PYRIDYL)]) -SER-TYR-(D- CIT -LEU-ARG-PRO-D-ALA-OH;Cetrorelixacetate;CETRORELIX;CETRORELIXACID;CETRIZINEDIHYDROCHLORIDE;ChemicalbookN-Acetyl-3-(2-naphthalenyl)-D-Ala-4-chloro-D-Phe-3-( 3-pyridyl) -D-Ala-L-Ser-L-Tyr-N5-(aminocarbonyl)-D-Orn-L-Leu-L-Arg-L-Pro-D-Ala-NH2;Cetrorelixum; Cetrorelixum.
Apejuwe
Cetrorelix acetate jẹ decapeptide sintetiki, eyiti o jẹ lilo ni pataki ni imọ-ẹrọ ibisi iranlọwọ lati ṣe idiwọ ovulation ti tọjọ ni awọn alaisan ti o ni itunnu ovarian iṣakoso.O jẹ atako homonu ti o tu silẹ gonadotropin (GnRH) ti o le dije pẹlu LHRH ailopin lati dipọ si awọn olugba lori awọ sẹẹli pituitary, nitorinaa ṣe idinamọ yomijade ti homonu luteinizing (LH) ati homonu iwuri follicle (FSH) nipasẹ pituitary ni iwọn lilo kan. - ọna ti o gbẹkẹle.
Cetrorelix acetate jẹ homonu ti o tu silẹ gonadotropin (GnRH).Ọja yii ti njijadu pẹlu GnRH endogenous fun awọn olugba lori awọn sẹẹli pituitary, nitorinaa ṣe idiwọ itusilẹ ti homonu luteinizing endogenous (LH) ati homonu stimulating follicle (FSH), idaduro hihan ti tente oke LH, nitorinaa iṣakoso ovulation.Ipa ti ọja yii jẹ igbẹkẹle iwọn lilo, ipa inhibitory jẹ taara, ati pe o wa ni itọju nipasẹ itọju ti nlọ lọwọ, laisi fa ilosoke ibẹrẹ ni iṣẹ ṣiṣe olugba progesterone ti o tẹle nipasẹ idinku.
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TOC ati Iṣaṣeṣe
TOC ati ifarakanra ti ipese akọkọ ati awọn aaye ipadabọ ni abojuto lorekore.TOC ni abojuto nipasẹ QC ni gbogbo ọsẹ.Iṣe adaṣe jẹ abojuto lori ayelujara ati gbasilẹ nipasẹ oniṣẹ ibudo omi mimọ lẹẹkan ni gbogbo wakati mẹrin.A ṣe abojuto adaṣe ni RO akọkọ, RO Atẹle, EDI ati aaye ipadabọ lapapọ ti eto pinpin.Sipesifikesonu ti omi mimọ wa ni aye ati ni ibamu si sipesifikesonu ti a ti sọ tẹlẹ eyiti ko ju 1.3 µs/cm ni 25°C (USP).Fun ipese akọkọ ati awọn aaye ipadabọ, idanwo ni kikun.Ti ṣe ni gbogbo ọsẹ, fun aaye lilo miiran ni yipo kaakiri, idanwo kikun ni a ṣe lẹẹkan ni oṣu kan.Idanwo ni kikun pẹlu awọn ohun kikọ, pH, iyọ, nitrite, amonia, iṣiṣẹ, TOC, awọn nkan ti kii ṣe iyipada, awọn irin eru, awọn opin microbial ati endotoxin kokoro-arun.
