Eptifibatide fun Itoju Arun Arun Arun Arunrawọn 188627-80-7
Apejuwe ọja
| Oruko | Eptifibatide |
| nọmba CAS | 188627-80-7 |
| Ilana molikula | C35H49N11O9S2 |
| Ìwúwo molikula | 831.96 |
| Nọmba EINECS | 641-366-7 |
| iwuwo | 1.60± 0.1 g/cm3 (Asọtẹlẹ) |
| Awọn ipo ipamọ | Ti di ninu gbigbẹ, fipamọ sinu firisa, labẹ -15 ° C |
Awọn itumọ ọrọ sisọ
Eptifibatideacetatesalt; Eptifibatide,MPA-HAR-Gly-Asp-Trp-Pro-Cys-NH2,MPAHARGDWPC-NH2,>99%;MAP-LYS-GLY-ASP-TRP-PRO-CYS-NH2;INTEGRELIN;Eptifibatide; (Aminoiminomethyl) -N2- (3-mercapto-1-oxopropyl-L-lysylglycyl-La-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide;MPA-HAR-GLY-ASP-TRP-PRO-CYS-NH2 (DISULFIDEBRIDGE,MPA1-CYS6).
Platelet Glycoprotein antagonist
Etifibatide (integrilin) jẹ aramada aramada polypeptide platelet glycoprotein IIb/IIIa antagonist olugba olugba, eyiti o ṣe idiwọ iṣakojọpọ platelet ati thrombosis nipa didi ipa ọna ti o wọpọ ti apapọ platelet.Ti a ṣe afiwe pẹlu monoclonal antibody abciximab, eptifibatide ni okun sii, itọsọna diẹ sii ati abuda kan pato si GPIIb/IIIa nitori wiwa ti aropo amino acid Konsafetifu kan-lysine lati rọpo arginine.Nitorinaa, o yẹ ki o ni ipa itọju ailera to dara ni itọju ilowosi ti iṣọn-ẹjẹ iṣọn-alọ ọkan nla.Platelet glycoprotein IIb/IIIa awọn oogun antagonist olugba ti ni idagbasoke pupọ, ati lọwọlọwọ awọn iru awọn igbaradi mẹta lo wa ti o le ṣee lo ni ile-iwosan ni kariaye, abciximab, eptifibatide ati tirofiban.).Iriri kekere ko wa ni lilo awọn antagonists olugba platelet glycoprotein GPIIb/IIIa ni Ilu China, ati pe awọn oogun to wa tun ni opin pupọ.Oogun kan ṣoṣo, tirofiban hydrochloride, wa lori ọja naa.Nitorinaa, platelet glycoprotein IIb tuntun ti ni idagbasoke./IIIa antagonists olugba jẹ dandan.Eptifibatide ti ile jẹ ọja afarawe ti a ṣe nipasẹ Chengdu Sino Biological Products Co., Ltd.
Iyasọtọ
Iyasọtọ ti Awọn oogun Ikopọ Antiplatelet
Awọn oogun apapọ Antiplatelet le pin ni aijọju si awọn ẹka mẹta: 1. Cyclooxygenase-1 (COX-1) inhibitors, gẹgẹbi aspirin.2. Idilọwọ awọn akojọpọ platelet ti a fa nipasẹ adenosine diphosphate (ADP), gẹgẹbi clopidogrel, prasugrel, cangrelor, ticagrelor, bbl awọn inhibitors olugba prostaglandin EP3, awọn paati kẹmika ti iṣelọpọ tuntun ati awọn ayokuro ti o munadoko lati oogun Kannada ibile.
