Sulfate Chondroitin fun Itọju Arun Arun Arun Arun, Arthritis ati Iwosan ti Awọn ọgbẹ Corneal Mimọ 98%
Alaye ọja
| Oruko | Chondroitin sulfate |
| nọmba CAS | 9007-28-7 |
| Ilana molikula | C13H21NO15S |
| Ìwúwo molikula | 463.36854 |
| Nọmba EINECS | 232-696-9 |
| Omi solubility | Tiotuka ninu omi |
| Mimo | 98% |
| Ibi ipamọ | Fipamọ ni iwọn otutu deede |
| Fọọmu | Lulú |
| Àwọ̀ | Funfun si pa-funfun |
| Iṣakojọpọ | PE apo + Aluminiomu apo |
Awọn itumọ ọrọ sisọ
poly-1 (2/3) -n-acetyl-2-amino-2-deoxy-3-o-beta-d-glucopyranurosyl-4- (6) sulfonyl-d-galactose;chondroitinpoly sulfate;chondroitin sulfates;chondroiti nsulfuricacid;chondroitin sulfuric acids;chonsurid;CSO; (5ξ) -2- (Carboxyamino) -2-deoxy-3-O-β-D-glucopyranuronosyl-4-O-sulfo-α-L-arabino-hexopyranose
Pharmacological Ipa
Apejuwe
Chondroitinsulfate (CS) jẹ mucopolysaccharide ekikan ti a fa jade ati ti a sọ di mimọ lati inu ẹran ara kerekere.Sulfate Chondroitin ni awọn ẹya oriṣiriṣi bii A, C, D, E, H ati K. Chondroitin sulfate ni iseda ni a rii pupọ julọ ni kerekere ẹranko, egungun ọfun, egungun imu (41% ninu awọn ẹlẹdẹ), bovine, septum ẹṣin ati trachea (ti o ni ninu 36% si 39%), awọn ara miiran gẹgẹbi awọn egungun ẹsẹ, awọn iṣan, awọ ara, cornea, ati bẹbẹ lọ tun wa ninu.Awọn akoonu ti kerekere ẹja jẹ ọlọrọ pupọ, gẹgẹbi 50% si 60% ninu egungun yanyan, ati pupọ diẹ ninu awọn ara asopọ.
Fun arun atherosclerotic iṣọn-alọ ọkan, awọn lipids ẹjẹ ti o pọ si ati idaabobo awọ, arteriosclerosis, angina pectoris, ischemia myocardial, infarction myocardial, bbl ninu awọn alaisan ti o ni arun ọkan iṣọn-alọ ọkan.
Pharmacological Action
Rapamycin (RAPA) ni awọn ipa ẹgbẹ kanna si FK506.Ni nọmba nla ti awọn idanwo ile-iwosan, awọn ipa ẹgbẹ rẹ ni a rii lati jẹ igbẹkẹle iwọn lilo ati iyipada, ati RAPA ni awọn abere itọju ailera ko ti rii lati ni nephrotoxicity pataki ati pe ko si hyperplasia gingival.Awọn majele akọkọ ati awọn ipa ẹgbẹ pẹlu: orififo, ọgbun, dizziness, ẹjẹ imu, ati irora apapọ.Awọn aiṣedeede yàrá pẹlu: thrombocytopenia, leukopenia, hemoglobin kekere, hypertriglyceridemia, hypercholesterolemia, hyperglycemia, awọn enzymu ẹdọ ti o ga (SGOT, SGPT), dehydrogenase lactate ti o ga, hypokalemia, Hypomagnesemia, ati bẹbẹ lọ. Awọn ipele fosifeti pilasima ni a ro pe o jẹ iyọkuro fosifeti gigun lati inu kidirin gbigbe nipasẹ itọju ailera ajẹsara ti o da lori RAPA.Gẹgẹbi awọn ajẹsara ajẹsara miiran, RAPA ni anfani ti o pọ si ti ikolu, pẹlu ifarahan ti a royin lati mu pneumonia pọ si ni pataki, ṣugbọn iṣẹlẹ ti awọn akoran opportunistic miiran ko yatọ si pataki si CsA.
Awọn Ipa Toxicological
Sulfate Chondroitin wa jakejado eniyan ati ẹran ara kerekere.Igbaradi oogun ni akọkọ ni awọn isomers meji ti chondroitin sulfate A ati chondroitin sulfate C, ati akoonu ti sulfate chondroitin ninu kerekere ti awọn ẹranko ti awọn oriṣiriṣi oriṣiriṣi ati awọn ọjọ-ori yatọ.Awọn ipa elegbogi rẹ jẹ bi atẹle: sulfate chondroitin le yọ awọn lipids ati lipoproteins kuro ninu ẹjẹ, yọ idaabobo awọ kuro ninu awọn ohun elo ẹjẹ ni ayika ọkan, ṣe idiwọ ati tọju atherosclerosis, ati mu iwọn iyipada ti awọn lipids ati awọn acids fatty ninu awọn sẹẹli pọ si.Sulfate Chondroitin le ṣe idiwọ daradara ati tọju arun ọkan iṣọn-alọ ọkan.O ni egboogi-atherosclerosis ati egboogi-atherogenic plaque Ibiyi ipa lori esiperimenta arteriosclerosis si dede;mu ki awọn ẹka iṣọn-ẹjẹ pọ si tabi san kaakiri legbekegbe ti atherosclerosis, ati pe o le mu iyara iṣọn-ẹjẹ iṣọn-alọ ọkan tabi embolism mu yara.Iwosan, isọdọtun ati atunṣe ti negirosisi myocardial tabi degeneration.O le mu biosynthesis ti ojiṣẹ sẹẹli ribonucleic acid (mRNA) ati deoxyribonucleic acid (DNA) pọ si ati ni ipa ti igbega iṣelọpọ sẹẹli.Iṣẹ ṣiṣe anticoagulant kekere.Sulfate Chondroitin ni ipa anticoagulant iwọntunwọnsi, ati ọkọọkan 1 miligiramu ti chondroitin sulfate A jẹ deede si iṣẹ anticoagulant ti 0.45U ti heparin.Iṣẹ-ṣiṣe anticoagulant yii ko dale lori antithrombin III lati ṣe ipa rẹ, o le ṣe iṣẹ ṣiṣe anticoagulant nipasẹ eto fibrinogen.Sulfate Chondroitin tun ni egboogi-iredodo, iwosan ọgbẹ onikiakia ati awọn ipa egboogi-egbogi.
